
Investigador por México
Miembro del SNI, Nivel 2
Telefono: 8342000
Ext. :7313
Correo: sergio.hidalgo@ipicyt.edu.mx
Selección de artículos de investigación
Publicaciones en el Science Citation Index
1.- Verónica Quilumba-Dutan, 1,a Clara Carreón-Álvarez, 2,3,a Víctor Sanabria-Ayala, 2, Sergio Hidalgo-Figueroa, 2 Swaroop Chakraborty 4 , Eugenia Valsami-Jones 4 , Rubén López- Revilla, 2, * and José Luis Rodríguez-López Assessment of phage-displayed peptides targeting cancer cell surface proteins: A comprehensive molecular docking study. JOURNAL OF PEPTIDE SCIENCE. (en impresión (aceptado))
2.- Jesús Alfredo Araujo-León 1 , Ivonne Sánchez-del Pino 2 , Rolffy Ortiz-Andrade 3 , Sergio Hidalgo-Figueroa 4 , Areli Carrera-Lanestosa 5 , Ligia Guadalupe Brito-Argáez 1 , Avel González-Sánchez 6 , Germán Giácoman-Vallejos 6 , Oswaldo Hernández-Abreu 7 , HPLC-Based Metabolomic Analysis and Characterization of Amaranthus cruentus Leaf and Inflorescence Extracts for Their Antidiabetic and Antihypertensive Potential. MOLECULES. 29: 24/2003
3.- Abraham Gutiérrez-Hernándeza, Samuel Estrada-Sotoa, Carlos Martínez-Condea, Emmanuel Gaona- Tovara, José L. Medina-Francob, Emanuel Hernández-Núñezc, Sergio Hidalgo-Figueroad, Patricia Castro-Morenoe, Maximiliano Ibarra-Barajase, and Gabriel Navarrete-Vaz Synthesis, biosimulation and pharmacological evaluation of benzimidazole derivatives with antihypertensive multitarget effect. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS . 110: 7/129879
4.- Maria L. Gonzalez-Rivera 1, , Juan Carlos Barragan-Galvez 1, , Deisy Gasca-Martínez 2 , Sergio Hidalgo-Figueroa 3 , Mario Isiordia-Espinoza 4 and Angel Josabad Alonso-Castro In Vivo Neuropharmacological Effects of Neophytadiene. MOLECULES. 28: 12/0
5.- Eunice Yáñez-Barrientos 1 , Juan Carlos Barragan-Galvez 2 , Sergio Hidalgo-Figueroa 3 , Alfonso Reyes-Luna 1 , Maria L. Gonzalez-Rivera 2 , David Cruz Cruz 1 , Mario Alberto Isiordia-Espinoza 4 , Martha Alicia Deveze-Álvarez 2, Clarisa Villegas Gómez 1,* Neuropharmacological Effects of the Dichloromethane Extract from the Stems of Argemone ochroleuca Sweet (Papaveraceae) and Its Active Compound Dihydrosanguinarine. PHARMACEUTICALS. 16: 20/1175
6.- Wendoline Rosiles-Alanis,1 Alejandro Zamilpa,2 Rebeca Garcı´a-Macedo,3 Miguel A. Zavala-Sa´nchez,4 Sergio Hidalgo-Figueroa,5 Beatriz Mora-Ramiro,6 Rube´n Roma´n-Ramos,6 Samuel E. Estrada-Soto,7 and Julio C. Almanza-Perez 4-Hydroxybenzoic Acid and b-Sitosterol from Cucurbita ficifolia Act as Insulin Secretagogues, Peroxisome Proliferator-Activated Receptor-Gamma Agonists, and Liver Glycogen Storage Promoters: In Vivo, . JOURNAL OF MEDICINAL FOOD. 25: 588596/6
7.- Fernando Calzada, Normand García-Hernández, Sergio Hidalgo Figueroa, Elihú Bautista, Elizabeth Barbosa, Claudia Velázquez, María Elena Hernández-Caballero Expanding the Study of the Cytotoxicity of Incomptines A and B against Leukemia Cells. MOLECULES . 27: 1687
8.- Francisco Valenzuela Zamudio 1, Sergio Nemorio Hidalgo-Figueroa 2, Rolffy Rubén Ortíz Andrade 3, Alan Javier Hernández Álvarez 4, Maira Rubi Segura Campos Identification of antidiabetic peptides derived from in silico hydrolysis of three ancient grains: Amaranth, Quinoa and Chia. FOOD CHEMISTRY. 394: 12/133479
9.- Chrystyan Iván Bustos-Gómez 1, Deisy Gasca-Martínez 2,* , Eunice Yáñez-Barrientos 3, Sergio Hidalgo-Figueroa 4 , Maria L. Gonzalez-Rivera 5, Juan Carlos Barragan-Galvez 5 , Juan Ramón Zapata-Morales 5, Mario Isiordia-Espinoza 6 , Alma Rosa Corrales-Escobo Neuropharmacological Activities of Ceiba aesculifolia (Kunth) Britten & Baker f (Malvaceae). PHARMACEUTICALS. 15: 20/1580
10.- Blanca Colin-Lozano 1,2, Héctor Torres-Gomez 1,3 , Sergio Hidalgo-Figueroa 1,4, Fabiola Chávez-Silva 1, Samuel Estrada-Soto 1 , Julio Cesar Almanza-Pérez 5 and Gabriel Navarrete-Vazquez Synthesis, In Vitro, In Vivo and In Silico Antidiabetic Bioassays of 4-Nitro(thio)phenoxyisobutyric Acids Acting as Unexpected PPAR Modulators: An In Combo Study. PHARMACEUTICALS. 15: 102
11.- Fernando Calzada, Elihú Bautista, Sergio Hidalgo-Figueroa, Normand García-Hernández, Claudia Velázquez, Elizabeth Barbosa, Miguel Valdes, Jesus Ivan Solares-Pascasio Understanding the Anti-Diarrhoeal Properties of Incomptines A and B: Antibacterial Activity against Vibrio cholerae and Its Enterotoxin Inhibition. PHARMACEUTICALS. 15: 196
12.- Fernando Calzada, Elihú Bautista, Sergio Hidalgo-Figueroa, Normand García-Hernández, Elizabeth Barbosa, Claudia Velázquez, Rosa María Ordoñez-Razo and Angel Giovanni Arietta-García Antilymphoma Effect of Incomptine A: In Vivo, In Silico, and Toxicological Studies. MOLECULES . 26: 6646
13.- Sergio Hidalgo-Figueroa a,*, Ana Rodríguez-Lu´evano b,1, Julio C. Almanza-P´erez c, Abraham Giacoman-Martínez d, Rolffy Ortiz-Andrade e, Ismael Le´on-Rivera f, Gabriel Navarrete-Vázquez g Synthesis, molecular docking, dynamic simulation and pharmacological characterization of potent multifunctional agent (dual GPR40-PPARγ agonist) for the treatment of experimental type 2 diabetes. EUROPEAN JOURNAL OF PHARMACOLOGY. 907: 12/174244 Número de citas: 16
14.- González-Juárez D, Escobedo-Moratilla A, Flores J, Hidalgo-Figueroa S, Martínez-Tagüeña N, Morales-Jiménez J, Muñiz-Ramírez A, Pastor-Palacios G, Pérez-Miranda S, Ramírez-Hernández A, Trujillo J, Bautista E A Review of the Ephedra genus: Distribution, Ecology, Ethnobotany, Phytochemistry and Pharmacological Properties. MOLECULES . 25: 3283
15.- Sánchez-Recillas, A., Navarrete-Vázquez, G., Hidalgo-Figueroa, S., (...), Yáñez-Pérez, V., Sánchez-Salgado, J.C. Pharmacological characterization of the cardiovascular effect of Nibethione: ex vivo, in vivo and in silico studies. JOURNAL OF PHARMACY AND PHARMACOLOGY. 72(9)
16.- . Rolffy Ortiz-Andrade 1 , Jesús Alfredo Araujo-León 2 3 , Amanda Sánchez-Recillas 1 , Gabriel Navarrete-Vazquez 4 , Avel Adolfo González-Sánchez 5 , Sergio Hidalgo-Figueroa, Ángel Josabad Alonso-Castro , Irma Aranda-González , Emanuel Hernández-Nú Toxicological Screening of Four Bioactive Citroflavonoids: In Vitro, In Vivo, and In Silico Approaches. MOLECULES . 25(24): 5959
17.- Viridiana Candelaria Pérez Nájera, Janet A. Gutiérrez-Uribe, Marilena Antunes Ricardo, Sergio Hidalgo Figueroa, Carmen Lizette Del Toro Sánchez, Luis A. Salazar-Olivo and Eugenia Lugo-Cervantes Smilax aristolochiifolia root extract and its compounds chlorogenic acid and astilbin inhibit the activity of a-amylase and a-glucosidase enzymes. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE. : 1-12
18.- Sergio Hidalgo-Figueroa · Samuel Estrada-Soto · Juan José Ramírez-Espinosa · Paolo Paoli · Giulia Lori · Ismael León-Rivera · Gabriel Navarrete-Vázquez Synthesis and Evaluation of Thiazolidine-2,4-dione/benzazole Derivatives as Inhibitors of Protein Tyrosine Phosphatase 1B (PTP-1B): Antihyperglycemic Activity with Molecular Docking Study . BIOMEDICINE & PHARMACOTHERAPY . 107: 1302-1310
19.- María Eva González-Trujano, Gerardo Uribe-Figueroa, Sergio Hidalgo-Figueroa, Ana Laura Martínez, Myrna Déciga-Campos, Gabriel Navarrete-Vazquez Synthesis and antinociceptive evaluation of bioisosteres and hybrids of naproxen, ibuprofen and paracetamol. BIOMEDICINE & PHARMACOTHERAPY . 101: 553-562
20.- Abraham Giacoman-Martínez, Francisco J. Alarcón-Aguilar, Alejandro Zamilpa, Sergio Hidalgo-Figueroa, Gabriel Navarrete-Vázquez, Rebeca García-Macedo, Rubén Román-Ramos, Julio C. Almanza-Pérez Triterpenoids from Hibiscus sabdariffa L. with PPARd/y dual agonist action: in vivo, in vitro and in silico studies. PLANTA MEDICA.
21.- Ricardo Guzman-Avila, Virginia Flores-Morales, Paolo Paoli, Guido Camici, Juan Jose Ramírez-Espinosa, Litzia Ceron-Romero, Gabriel Navarrete-Vazquez, Sergio Hidalgo-Figueroa, Maria Yolanda Rios, Rafael Villalobos-Molina, Samuel E Soto Ursolic acid derivatives as potential antidiabetic agents: In vitro, in vivo, and in silico studies. DRUG DEVELOPMENT RESEARCH . : 1-11 Número de citas: 1
22.- Sergio Hidalgo-Figueroa, Gabriel Navarrete-Vázquez, Samuel Estrada-Soto, Diana Giles-Rivas, Francisco J. Alarcón-Aguilar, Ismael León-Rivera, Abraham Giacoman-Martínez, Elizabeth Miranda Pérez, Julio C. Almanza-Pérez Discovery of new dual PPARγ-GPR40 agonists with robust antidiabetic activity: Design, synthesis and in combo drug evaluation.. BIOMEDICINE & PHARMACOTHERAPY . 90: 53-61 Número de citas: 5
23.- Angélica Flores-Flores, Sergio Hidalgo-Figueroa, Rafael Villalobos-Molina , Maximiliano Ibarra-Barajas , Blanca Bazán-Perkins, Gabriel Navarrete-Vázquez, Samuel Estrada-Soto Relaxant effect of structurally related flavonoids on isolated tracheal rat rings: a SAR study. MEDICINAL CHEMISTRY RESEARCH . 27: 122-127
24.- Jorge Alberto Garcia-Diaz, Gabriel Navarrete-Vázquez, Sara Garcia-Jimenez, Sergio Hidalgo-Figueroa, Julio C. Almanza-Pérez, Francisco Javier Alarcon-Aguilar, Jaime Gómez-Zamudio, Miguel Cruz, Maximiliano Ibarra-Barajas, Samuel Estrada-Soto Antidiabetic, antihyperlipidemic and anti-inflammatory effects of tilianin in streptozotocin-nicotinamide diabetic rats. BIOMEDICINE & PHARMACOTHERAPY . 83: 667-675 Número de citas: 8
25.- Navarrete-Vázquez G.; Austrich-Olivares A.; Godínez-Chaparro B.; Hidalgo-Figueroa S.; Estrada-Soto S.; Hernández-Núñez E.; Torres-Gómez H.; Schepmanne D.; Wünsche B Discovery of 2-(3,4-dichlorophenoxy)-N-(2-morpholin-4-ylethyl) acetamide: A selective σ1 receptor ligand with antinociceptive effect. . BIOMEDICINE & PHARMACOTHERAPY . 79: 284-293 Número de citas: 3
26.- Cerón-Romero L.; Paoli P.; Camici G.; Flores-Morales V.; Yolanda Rios M.; Ramírez-Espinosa J. J.; Hidalgo-Figueroa S.; Navarrete-Vázquez G.; Estrada-Soto S In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives. BIOORGANIC & MEDICINAL CHEMISTRY . 26(8): 2018-2022 Número de citas: 8
27.- Navarrete-Vázquez G.; Chávez-Silva F.; Colín-Lozano B.; Estrada-Soto S.; Hidalgo-Figueroa S.; Guerrero-Álvarez J.; Méndez ST.; Reyes-Vivas H.; Oria-Hernández J.; Canul-Canché J.; Ortiz-Andrade R..; Moo-Puc R. Synthesis of nitro(benzo)thiazole acetamides and in vitro antiprotozoal effect against amitochondriate parasites Giardia intestinalis and Trichomonas vaginalis. BIOORGANIC & MEDICINAL CHEMISTRY . 23: 2204-2210 Número de citas: 10
28.- Navarrete-Vázquez, G.; Morales-Vilchis, M. G.; Estrada-Soto, S.; Ramírez-Espinosa, J. J.; Hidalgo-Figueroa, S.; Nava-Zuazo, C.; Tlahuext, H.; León-Rivera, I.; Medina-Franco, J. L.; López-Vallejo, F.; Webster, S. P.; Binnie, M.; Ortiz-Andrade, R.; More . Synthesis of 2-{2-[(alpha/beta-naphthalen-1-ylsulfonyl)amino]-1,3-thiazol-4-yl} acetamides with 11 beta-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities . EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 74: 179-186 Número de citas: 10
29.- Sánchez-Recillas, A.; Navarrete-Vázquez, G.; Hidalgo-Figueroa, S.; Yolanda Ríos, M.; Ibarra-Barajas, M.; Estrada-Soto, S Semisynthesis, ex vivo evaluation, and SAR studies of coumarin derivatives as potential antiasthmatic drugs. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 77: 400-408 Número de citas: 25
30.- Ramírez-Espinosa, J.J.; Ríos, M. Y.; Paoli, P.; Flores-Morales, V.; Camici, G.; de la Rosa-Lugo, V.; Hidalgo-Figueroa S.; Navarrete-Vázquez, G.; Estrada-Soto S Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silicostudies for PTP-1B inhibition. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 87: 316-327 Número de citas: 17
31.- Navarrete-Vázquez, G.; Torres-Gómez H.; Hidalgo-Figueroa, S.; Ramírez-Espinosa, J. J.; Estrada-Soto, E Synthesis, in vitro and in silico studies of a PPARand GLUT-4 modulator with hypoglycemic effect. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS . 24: 4575-4579 Número de citas: 12
32.- Ávila-Villarreal, G.; Hernández-Abreu, O.; Hidalgo-Figueroa, S.; Navarrete-Vázquez, G.; Escalante-Erosa, F.; Peña-Rodríguez, L. M.; Villalobos-Molina, R.; Estrada-Soto, S Antihypertensive and vasorelaxant effects of dihydrospinochalcone-A isolated from Lonchocarpus xuul Lundell by NO production: Computational and ex vivo approaches. PHYTOMEDICINE. 20(14): 1241-1246 Número de citas: 10
33.- Hidalgo-Figueroa, S.; Ramírez-Espinosa, J. J.; Estrada-Soto, S.; Almanza-Pérez, J. C.; Román-Ramos, R.; Alarcón-Aguilar, F. J.; Hernández-Rosado, J. V.; Moreno-Díaz, H.; Díaz-Coutiño, D.; Navarrete-Vázquez, G Discovery of thiazolidine-2,4-dione/biphenylcarbonitrile hybrid as dual ppar modulator with antidiabetic effect: in vitro, in silico and in vivo approaches. CHEMICAL BIOLOGY & DRUG DESIGN. 81(4): 474-483 Número de citas: 26
34.- Navarrete-Vázquez, G.;* Alaniz-Palacios, A.; Hidalgo-Figueroa, S.; González Acevedo, C.; Ávila Villarreal, G.; Estrada-Soto, S.; Webster S.; Medina-Franco, J. L.; López-Vallejo, F.; Guerrero-Alvarez, J.; Tlahuext, H Discovery, synthesis and in combo studies of a tetrazole analogue of clofibric acid as a potent hypoglycemic agent. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS . 23(11): 3244-3247 Número de citas: 12
35.- M. Y. Rios, S. López-Martínez, F. López-Vallejo, J. L. Medina-Franco, R. Villalobos-Molina, M. Ibarra-Barajas, G. Navarrete-Vazquez, S. Hidalgo-Figueroa, O. Hernández-Abreu, S. Estrada-Soto Vasorelaxant activity of some structurally related triterpenic acids from Phoradendron reichenbachianum (Viscaceae) mainly by NO production: ex vivo and in silico studies. FITOTERAPIA. 83(6): 1023-1029 Número de citas: 10
36.- Navarrete-Vázquez, G.; Hidalgo-Figueroa, S.; Torres-Piedra, M.; Vergara-Galicia, J.; Rivera-Leyva, J. C.; Estrada-Soto, S.; León-Rivera, I.; Aguilar-Guardarrama, B.; Rios-Gómez, Y.; Villalobos-Molina, R.; Ibarra-Barajas, M. Synthesis, vasorelaxant activity and antihypertensive effect of benzo[d]imidazole derivatives. BIOORGANIC & MEDICINAL CHEMISTRY . 18(11): 3985-3991 Número de citas: 16
37.- Navarrete-Vázquez, G.; Torres Gómez, H.; Hidalgo-Figueroa, S.; Tlahuext, H 2-Methyl-2-(4-nitrophenoxy)propanoic acid. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE. E64: o2261. Número de citas: 2
Publicaciones en otros índices internacionales
1.- Carlos E. Castillo-Espinoza 1, María Leonor González-Rivera 2 , Alberto Medina-Ortiz 1 , Juan Carlos Barragan-Galvez 2 , Sergio Hidalgo-Figueroa 3 , David Cruz Cruz 1 , Martha Alicia Deveze-Alvarez 2, Gerardo González-García 1 , Clarisa Villegas Gómez 1,* Anxiolytic-like and Antidepressant Effects of a 13H-indolo[2,3-a]thiopyrano[2,3-g]quinolizine Derivative. Chemistry.6 : 10/2024
2.- Ana Rodríguez-Luévano,[a] Julio C. Almanza-Pérez,[b] Rolffy Ortiz-Andrade,[c] Samuel Lara-González,[d] Rosa Santillán,[e] Gabriel Navarrete-Vázquez,[f] Abraham Giacoman-Martínez,[b, g] Roberto C. Lazzarini-Lechuga,[h] Elihú Bautista,[i] and Sergio Hidalgo Discovery of Palindrome Dual PPARγ-GPR40 Agonists for Treating Type 2 Diabetes. ChemMedChem .19 : 15/e202400492
3.- Nidia del Carmen Quintal Bojórquez, Luis Fernando Morales Mendoza, Sergio Hidalgo-Figueroa, Alan Javier Hernández Álvarez & Maira Rubi Segura Campos In silico analysis of the interaction of de novo peptides derived from Salvia hispanica with anticancer targets. Journal of Biomolecular Structure and Dynamics.42 : 15/
4.- Angel Josabad Alonso‑Castro, Amanda Sánchez‑Recillas · Sergio Hidalgo‑Figueroa · Cesar Rogelio Solorio‑Alvarado · Mario Alberto Isiordia‑Espinoza· Samuel Enoch Estrada‑Soto · Marcos Bonilla‑Hernández · Rolffy Rubén The Antidiarrheal Activity of Octacosanol is Mediated by the Possible Participation of α2 Adrenoreceptors. Revista Brasileira de Farmacognosia.33 : 6
5.- Ismael León-Rivera, Juana Villeda-Hernández, Elizur Montiel-Arcos, Isaac Tello, María Yolanda Rios, Samuel Estrada-Soto, Angélica Berenice Aguilar, Verónica Núñez-Urquiza, Jazmín Méndez-Mirón, Victoria Campos-Peña, Sergio Hidalgo-Figueroa, EvaHernández, Neuroprotective Effects of Ganoderma curtisii Polysaccharides After Kainic Acid-Seizure Induced.(en impresión (aceptado))
Publicaciones en revistas no indizadas
1.- Méndez-Cuesta CA, Herrera-Rueda MÁ, Hidalgo-Figueroa S, Tlahuext H, Moo-Puc R, Chale-Dzul JB, Chan-Bacab M, Ortega-Morales BO, Hernández-Núñez E, Méndez-Lucio O, Medina-Franco JL, Navarrete-Vazquez G Synthesis, Screening and in silico Simulations of Anti-Parasitic Propamidine/Benzimidazole Derivatives. Medicinal Chemistry.3(2) : 137-148
2.- González-Trujano, M. E.; Ponce-Muñoz, H.; Hidalgo-Figueroa, S.; Navarrete-Vázquez, G.; Estrada-Soto, S Depressant effects of Agastache mexicana methanol extract and one of the major metabolites tilianin. Asian Pacific Journal of Tropical Medicine.3 : 185-190